Essential Duties and Responsibilities
- Establish NSG animal models for in vivo testing of CAR-T, CAR-NK and other cell therapy productcandidates.
- Establish in vivo assays for functional analysis of CAR-T, CAR-NK cells.
- Establish and maintain cancer cell lines for in vitro and in vivo assays.
- Write and review in vivo studies protocols, schedules and coordinate with study directors
- Manage vivarium operations and CRO relations, including equipment and consumables.
- Manage, and keep animal protocols updated for new cancer models and study procedures.
- Perform tumor burden measurements by volume and live animal imaging.
- Maintain organized, detailed records to support internal documentation and regulatory requirements.
Skills and Competencies
- Must have routinely performed xenograft cancer models using NSG or similar mouse strains.
- Must have live animal imaging system experience
- Experience in administering CAR-NK or CAR- T cells to mouse models.
- Experience in monitoring animal health, GVHD, and tumor growth.
- Experience in isolating immune cells from tumor and tissues.
- Knowledge and experience with allogeneic CAR-NK or CAR-T is preferred.
- Able to work independently as well as in a team with diverse background.
- Able to collect, analyze and present data to the research and management teams.
- Strong written and verbal communication skills, and detailed record keeping skills.
- A can-do attitude and an ability to adapt to evolving priorities.
.Educational Requirement
- Ph.D., MS. or BS. in Immunology, Bioengineering, Biology, Animal Sciences, or related fields with over 4years of cell therapy in vivo model-related academic or industry experience.
Overland Compensation and Benefits:
- The expected salary range for this position based in South San Francisco is $70,000~$120,000. The pay ultimately offered will be determined based on job-related qualifications, education, experience, and other job-related factors permitted by law.
Equal Employment Opportunity:
- Overland is an equal opportunity employer and values diversity at our company. We do not discriminate based on race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Job Type: Full-time
Pay: $70,000.00 - $120,000.00 per year
Schedule:
Application Question(s):
- When do you plan to start a new job?
- Will you now, or in the future, require sponsorship for employment visa status?
- What are your expectations
Ability to Commute:
- South San Francisco, CA 94080 (Preferred)
Work Location: In person